Drostanolone propionate is an injectable anabolic/androgenic steroid (AAS). It is highly androgenic and mildly anabolic. Drostanolone does not aromatize into estrogens and has similar properties to dihydrotestosterone (DHT).

Drostanolone originally was developed to be used as an anti-estrogenic compound for treating female breast cancer. Drostanolone is irreversibly metabolized by the enzyme 3a-hydroxysteroid-dehydrogenase into an inactive form of 2α-methyl-5α-androstan-3α-ol-17-one.