As an AI Anastrozole functions by blocking the aromatase enzyme, which is in turn responsible for the production of estrogen. By inhibiting the aromatase process, Anastrozole will lower the body’s serum estrogen levels; in fact, a total suppression of estrogen by 80% has been well noted with this AI.Anastrozole also has the ability to stimulate the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones essential to natural testosterone production.