Nandrofen (Nandrolone Phenylpropionate) is an injectable form of the anabolic steroid nandrolone.

Nandrofen (Nandrolone Phenylpropionate) is highly favored by athletes for its ability to promote significant strength and lean muscle mass gains without strong androgenic or estrogenic side effects.

Estrogenic Side Effects

Nandrofen (Nandrolone Phenylpropionate) has a low tendency for estrogen conversion. Consequently, estrogen-related side effects are a much lower concern with this drug than with testosterone. Elevated estrogen levels may still be noticed with higher dosing, and may cause side effects such as increased water retention, body fat gain and gynecomastia.

The use of an anti-estrogen is often sufficient to mitigate gynecomastia caused by progestational anabolic/androgenic steroids.

Androgenic Side Effects

Although classified as an anabolic steroid, androgenic side effects are still common with this substance, especially with higher doses. This may include bouts of oily skin, acne, and body/facial hair growth.

Anabolic/androgenic steroids may also aggravate male pattern hair loss.

Women are also warned of the potential virilizing effects of anabolic/androgenic steroids. These may include a deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.

Hepatotoxicity Side Effects

Nandrofen (Nandrolone Phenylpropionate) does not have hepatotoxic effects and therefore, liver toxicity is unlikely.

Cardiovascular Side Effects

Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to reduce HDL (good) cholesterol values and increase LDL (bad) cholesterol values, which may shift the HDL to LDL balance in a direction that favors greater risk of arteriosclerosis.

The relative impact of an anabolic/androgenic steroid on serum lipids is dependant on the dose, route of administration (oral vs. injectable), type of steroid (aromatizable or non-aromatizable), and level of resistance to hepatic metabolism.

Anabolic/androgenic steroids may also adversely affect blood pressure and triglycerides, reduce endothelial relaxation, and support left ventricular hypertrophy, all potentially increasing the risk of cardiovascular disease and myocardial infarction.

Nandrofen (Nandrolone Phenylpropionate) is likely to have a less dramatic impact on cardiovascular risk factors than synthetic oral anabolic steroids.

To help reduce cardiovascular strain, it is advised to maintain an active cardiovascular exercise program and minimize the intake of saturated fats, cholesterol, and simple carbohydrates at all times during active steroid administration. Supplementing with fish oils and a natural cholesterol/antioxidant formula is also recommended.

Testosterone Suppression

All anabolic/androgenic steroids are expected to suppress endogenous testosterone production. Testosterone is the primary male androgen, and offers strong negative feedback on endogenous testosterone production.

Testosterone-based drugs will, likewise, have a strong effect on the hypothalamic regulation of natural steroid hormones. Without the intervention of testosterone-stimulating substances, testosterone levels should return to normal within 2-6 months of drug secession.

Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse, necessitating medical intervention.

Administration for Men

It is most commonly used at a dosage of 200 – 400 mg per week. Due to the fast acting nature of the phenylpropionate ester, the weekly dosage should be further divided to two separate applications spaced evenly apart. One should also take caution to rotate injection sites regularly, so as to avoid irritation or infection.